Product Overview
Description
CLPP-00150926 is recombinant human NUBP2 protein
Applications
Mass Spectrometry, SDS-PAGE
Protein Length
Full length protein
Nature
Recombinant Protein
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMEAAAEPGNLAGVRHIILVLSGKGGVGKSTISTELALALRHAGKKVGILDVDLCGPSIPRMLGAQGRAVHQCDRGWAPVFLDREQSISLMSVGFLLEKPDEAVVWRGPKKNALIKQFVSDVAWGELDYLVVDTPPGTSDEHMATIEALRPYQPLGALVVTTPQAVSVGDVRRELTFCRKTGLRVMGIVENMSGFTCPHCTECTSVFSRGGGEELAQLAGVPFLGSVPLDPALMRTLEEGHDFIQEFPGSPAFAALTSIAQKILDATPACLP
Sequence Similarities
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
Predicted Molecular Weight
31 kDa including tags
Target Information
Alternative Names
C447E6.1 (nucleotide binding protein 1 (E.coli MinD like) ); CFD1; Cytosolic Fe-S cluster assembly factor NUBP2; D17Wsu11e; Homolog of yeast cytosolic FeS cluster deficient 1; NBP 2; NUBP1; Nubp2; NUBP2_HUMAN; Nucleotide binding protein 2; Nucleotide binding protein 2 (E.coli MinD like); Nucleotide binding protein 2 (MinD homolog, E. coli); Nucleotide-binding protein 2
Protein Function
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.
Tissue Specificity
Widely expressed with highest expression in skeletal muscle.
Shipping & Handling
Constituents
0.02% DTT, 50% Glycerol (glycerin, glycerine), 49% PBS.
Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.