Recombinant Human KCTD13 Protein

Cat. No.: CLPP-00150803

Product Size: 20 µg Custom size

Product Overview

Description
CLPP-00150803 is recombinant human KCTD13 protein, Tagged
Purity
> 87%
Applications
SDS-PAGE
Protein Length
Full length protein
Animal Free
No
Nature
Recombinant Protein
Species
Human
Form
Liquid
Sequence
SAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD
Sequence Similarities
Belongs to the BACURD family. Contains 1 BTB (POZ) domain.
Predicted Molecular Weight
63 kDa
Tags
GST tag N-Terminus

Target Information

Protein Name
KCTD13
UniProt No.
Alternative Names
BACD1_HUMAN; BACURD1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; BTB/POZ domain-containing protein KCTD13; FKSG86; hBACURD1; KCTD13; PDIP1; POLDIP 1; POLDIP1; Polymerase delta-interacting protein 1; Potassium channel tetramerisation domain containing 13; PP6832; TNFAIP1 like polymerase delta interacting protein 1; TNFAIP1-like protein
Protein Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.
Tissue Specificity
Expressed in a wide variety of tissues.
Involvement in Disease
The gene represented in this entry may act as a disease modifier for autism and schizophrenia associated with recurrent deletions and duplications of chromosome 16p11.2 region.

Shipping & Handling

pH
pH: 8.0
Constituents
0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 20% Glycerol (glycerin, glycerine).
Shipping
Shipped on Dry Ice.
Storage
Store at -80 °C.

For Research Use Only. Not For Clinical Use.

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