Product Overview
Description
CLPP-00150705 is recombinant human GALK1 protein
Applications
HPLC, SDS-PAGE
Protein Length
Full length protein
Nature
Recombinant Protein
Endotoxin Level
< 0.100 Eu/µg
Sequence
MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL
Sequence Similarities
Belongs to the GHMP kinase family. GalK subfamily.
Predicted Molecular Weight
42 kDa
Target Information
Alternative Names
EC 2.7.1.6; epididymis secretory protein Li 19; Galactokinase; Galactokinase 1; Galactose kinase; GALK; GALK 1; GALK1; GALK1_HUMAN; GK1; GLK; GLK1; HEL-S-19
Protein Function
Catalyzes the transfer of a phosphate from ATP to alpha-D-galactose and participates in the first committed step in the catabolism of galactose.
Involvement in Disease
Defects in GALK1 are the cause of galactosemia II (GALCT2). Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
Shipping & Handling
Constituents
0.88% Sodium chloride, 0.32% Tris HCl. Supplied as a 0.2 µM filtered solution.
Shipping
Shipped on Dry Ice.
Storage
Store at -20 °C or -80 °C.
