Product Overview
Description
CLPP-00150689 is recombinant human FSTL1 protein, Active
Applications
Functional Studies, HPLC, SDS-PAGE
Protein Length
Full length protein
Nature
Recombinant Protein
Sequence
EEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKTKRVSTKEI
Sequence Similarities
Contains 2 EF-hand domains. Contains 1 follistatin-like domain. Contains 1 Kazal-like domain. Contains 1 VWFC domain.
Predicted Molecular Weight
33 kDa
Target Information
Alternative Names
Anti FSTL1; FLJ50214; FLJ52277; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1 antibody; FSTL1_HUMAN; Micro RNA 198; MIR198; miRNA198 included; OCC 1; OCC1
Protein Function
Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (By similarity). Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (By similarity). Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
Tissue Specificity
Overexpressed in synovial tissues from rheumatoid arthritis.
Shipping & Handling
Constituents
0.16% Sodium phosphate.
Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.
