Product Overview
Description
CLPP-00150677 is recombinant human FLG protein, His tag
Protein Length
Protein fragment
Nature
Recombinant Protein
Sequence
DSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAFGKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQRYYYYE
Sequence Similarities
Belongs to the S100-fused protein family. Contains 2 EF-hand domains. Contains 23 filaggrin repeats.
Predicted Molecular Weight
27 kDa including tags
Target Information
Alternative Names
ATOD2; Epidermal filaggrin; FILA_HUMAN; Filaggrin; Filaggrin precursor; Fillagrin; FLG; Profilaggrin
Protein Function
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
Tissue Specificity
Keratohyalin granules.
Involvement in Disease
Ichthyosis vulgarisDermatitis atopic 2.
Shipping & Handling
Constituents
Tris buffer, 50% Glycerol (glycerin, glycerine).
Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.
