Product Overview
Description
CLPP-00150520 is recombinant human CCNY protein, Tagged
Applications
SDS-PAGE, Western Blot
Protein Length
Full length protein
Nature
Recombinant Protein
Sequence
GNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTDVREKRKSLFINHHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRLCEDKYKDLRRSARKRSASADNLTLPRWSPAIIS
Sequence Similarities
Belongs to the cyclin family. Cyclin Y subfamily. Contains 1 cyclin N-terminal domain.
Predicted Molecular Weight
65 kDa including tags
Target Information
Alternative Names
C10orf9; CBCP1; CCNX; Ccny; CCNY_HUMAN; CFP1; Chromosome 10 open reading frame 9; Cyc-Y; Cyclin box carrying protein 1; Cyclin box protein 1; Cyclin fold protein 1; Cyclin X; Cyclin Y; cyclin-X; Cyclin-Y
Protein Function
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Tissue Specificity
Widely expressed.
Shipping & Handling
Constituents
0.79% Tris HCl, 0.29% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine).
Shipping
Shipped on Dry Ice.
