Product Overview
Description
CLPP-00150475 is recombinant human CFL1 protein
Applications
SDS-PAGE, Western Blot
Protein Length
Full length protein
Nature
Recombinant Protein
Sequence
MGSSHHHHHHSSGLVPRGSHMASGVAVSDGVIKVFNDMKV
RKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDV
GQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLV
FIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCY
EEVKDRCTLAEKLGGSAVISLEGKPL
Sequence Similarities
Belongs to the actin-binding proteins ADF family. Contains 1 ADF-H domain.
Target Information
Alternative Names
18 kDa phosphoprotein; CFL; CFL 1; CFL1; COF1_HUMAN; Cofilin; Cofilin 1; Cofilin 1 non muscle; Cofilin non muscle isoform; Cofilin-1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18
Protein Function
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
Tissue Specificity
Widely distributed in various tissues.
Shipping & Handling
Shipping
Shipped at 4 °C.
Constituents
0.242% Tris, 10% Glycerol (glycerin, glycerine).
