Recombinant Human CNMD Protein

Cat. No.: CLPP-00150824

Product Size: 100 µg Custom size

Product Overview

Description
CLPP-00150824 is recombinant human CNMD protein, denatured
Purity
> 90%
Applications
SDS-PAGE
Protein Length
Full length protein
Animal Free
No
Nature
Recombinant Protein
Species
Human
Form
Liquid
Sequence
MGSSHHHHHHSSGLVPRGSHMGSREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
Predicted Molecular Weight
16 kDa including tags
Sequence Similarities
Belongs to the chondromodulin-1 family. Contains 1 BRICHOS domain.
Tags
His tag N-Terminus

Target Information

Protein Name
CNMD
Alternative Names
BRICD3; BRICHOS domain containing 3; CH-SP; CHM I; ChM-I; CHM1; chondromodulin; Chondromodulin I; Chondromodulin-1; Chondromodulin-I; Chondrosurfactant protein; LECT 1; Lect1; LECT1_HUMAN; Leukocyte cell derived chemotaxin 1; Multiple myeloma tumor suppressor 1; MYETS1
Protein Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
UniProt No.
Tissue Specificity
Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.

Shipping & Handling

Shipping
Shipped at 4 °C.
Storage
Store at -20 °C or -80 °C.
Constituents
0.32% Tris HCl, 2.4% Urea, 10% Glycerol (glycerin, glycerine).
pH
pH: 8.0

For Research Use Only. Not For Clinical Use.

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