Recombinant Human CEP55 Protein

Cat. No.: CLPP-00150110

Product Size: 50 µg Custom size

Product Overview

Description
CEP55 protein is a recombinant human CEP55 produced in E. coli with His, N-Terminal tag(s).
Purity
> 80%
Nature
Recombinant Protein
Species
Human
Endotoxin Level
Not Tested
Sequence
MSSRSTKDLIKSKWGSKPSNSKSETTLEKLKGEIAHLKTSVDEITSGKGKLTDKERHRLLEKIRVLEAEKEKNAYQLTEKDKEIQRLRDQLKARYSTTTLLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKARNQITQLESLKQLHEFAITEPLVTFQGETENREKVAASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCSK
Predicted Molecular Weight
54 kDa
Tags
His, N-Terminal

Target Information

Protein Name
CEP55
UniProt No.
Alternative Names
CEP55; Cancer/testis antigen 111; Centrosomal protein of 55 kDa; C10orf3; CT111; Centrosomal protein 55kDa; URCC6; Up-regulated in colon cancer 6
Protein Function
Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not required for microtubule nucleation. Plays a role in the development of the brain and kidney.
Involvement in Disease
Multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly (MARCH): An autosomal recessive, congenital disease characterized by severe hydranencephaly with multinucleated neurons, renal aplasia or dysplasia, and hypoplastic kidneys. Hydranencephaly is an anomaly leading to replacement of the cerebral hemispheres with a fluid-filled cyst. MARCH results in death in utero or in the perinatal period. The disease is caused by variants affecting the gene represented in this entry.

Shipping & Handling

Constituents
Supplied in 25 mM Tris. HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Shipping
Shipped on dry ice.
Storage
Store at -80 °C for up to 1 year.

For Research Use Only. Not For Clinical Use.

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