Recombinant Human ARPP19 Protein

Cat. No.: CLPP-00150284

Product Size: 50 µg Custom size

Product Overview

Description
CLPP-00150284 is recombinant human ARPP19 protein, Tagged
Purity
> 80%
Applications
SDS-PAGE
Protein Length
Full length protein
Animal Free
No
Nature
Recombinant Protein
Species
Human
Form
Liquid
Sequence
MSAEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAAPDKTEVTGDHIPTPQDLPQRKPSLVASKLAG
Sequence Similarities
Belongs to the endosulfine family.
Tags
GST tag N-Terminus

Target Information

Protein Name
ARPP19
UniProt No.
Alternative Names
ARP19; ARP19_HUMAN; ARPP-19; Arpp19; cAMP-regulated phosphoprotein 19
Protein Function
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.

Shipping & Handling

pH
pH: 7.5
Constituents
0.79% Tris HCl, 0.87% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine).
Shipping
Shipped on Dry Ice.
Storage
Store at -80 °C.

For Research Use Only. Not For Clinical Use.

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