Recombinant DYNLL1 / PIN Rabbit Monoclonal Antibody

Cat. No.: CLAB-00231494

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Clonality
Monoclonal
Host Species
Rabbit
Conjugation
APC
Applications
Antibody labelling, Target binding affinity
Clone Number
EP1660Y

Target Information

Target Name
DYNLL1
UniProt No.
Gene ID
Alternative Names
8 kDa dynein light chain; 8kDLC; Cytoplasmic dynein light polypeptide; DLC1; DLC8; DNCL1; DNCLC1; DYL1_HUMAN; Dynein , cytoplasmic, light chain 1; Dynein light chain 1 cytoplasmic; Dynein light chain 1, cytoplasmic; Dynein light chain LC8 type 1; Dynein light chain LC8-type 1; Dynein, cytoplasmic, light polypeptide 1; Dynein, light chain, LC8-type 1; DYNLL1; HDLC1; LC8; LC8a; MGC126137; MGC126138; MGC72986; PIN; Protein inhibitor of neuronal nitric oxide synthase; Protein inhibitor of neuronal NOS
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
Tissue Specificity
Ubiquitous.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at 4 °C. Store In the Dark.
Storage Buffer
98% PBS, 1% BSA. pH: 7.40.
Preservative
0.02% Sodium Azide

For Research Use Only. Not For Clinical Use.

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