Product Overview
Description
CEP72 is a centrosomal protein that belongs to the leucine-rich-repeat (LRR) superfamily of proteins. The specific function of CEP72 has not been characterized.
Applications
Antibody Competition
Nature
Recombinant Protein
Sequence
SVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQELKKTMALF
Predicted Molecular Weight
27 kDa
Target Information
Alternative Names
Centrosomal protein 72kDa; Centrosomal protein of 72 kDa; Cep72; KIAA1519FLJ10565; MGC5307
Protein Function
Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2.
Shipping & Handling
Constituents
PBS and 1M Urea, pH 7.4.
Shipping
Shipped on dry ice.
