Product Overview
Description
Centrosomal protein of 192 kDa (CEP192) has been shown to be required for centrosomes maturation and spindle assembly. In this process, CEP192 functions as scaffolding for microtubule nucleation during mitosis.
Applications
Antibody Competition
Nature
Recombinant Protein
Sequence
KGVDESGDVFRATYAAFRCSPISGLLESHGIQKVSITFLPRGRGDYAQFWDVECHPLKEPHMKHTLRFQLSGQSIEAENEPENACLSTDSLI
Predicted Molecular Weight
28 kDa
Target Information
Alternative Names
Centrosomal protein 192kDa; Centrosomal protein of 192 kDa; Cep192; FLJ10352; KIAA1569
Protein Function
Required for mitotic centrosome maturation and bipolar spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Centrosome-specific activating scaffold for AURKA and PLK1.
Shipping & Handling
Constituents
PBS and 1M Urea, pH 7.4.
Shipping
Shipped on dry ice.
