Product Overview
Reactivity
Human (predicted: Mouse, Rat)
Applications
Flow Cyt (Intra)
Target Information
Alternative Names
CDC42; CDC42_HUMAN; CDC42Hs; Cell division control protein 42 homolog; Cell division cycle 42 (GTP binding protein 25kDa); Cell division cycle 42; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; Growth regulating protein; GTP binding protein 25kDa; Small GTP binding protein CDC42; TKS
Function
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Causes the formation of thin, actin-rich surface projections called filopodia.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Upon delivery aliquot. Store at 4 °C. Store In the Dark.
Storage Buffer
1% BSA, PBS. pH: 7.40.
Preservative
0.02% Sodium Azide
