Product Overview
Reactivity
Human, Mouse, Rat (predicted: Pig)
Applications
ICC/IF, IHC-P, WB
Target Information
Alternative Names
Axil; Axin like protein; Axin-2; Axin-like protein; Axin2; AXIN2_HUMAN; Axis inhibition protein 2; Conductin; DKFZp781B0869; MGC10366; MGC126582
Function
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.
Tissue Specificity
Expressed in brain and lymphoblast.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C. Do Not Freeze.
Storage Buffer
PBS. pH: 7.20.
