Product Size
25 mg
5 mg
Custom Size
Product Overview
Description
Cell-permeable, non-selective and reversible DUB inhibitor.
Biological Description
Cell-permeable, non-selective and reversible DUB inhibitor (IC50 values are 5 to 20 μM). Induces polyubiquitinated protein accumulation in cells without directly affecting proteasome activity. Activates autophagy.
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
Thiocyanic acid 2,6-diamino-3,5-pyridinediyl ester
Molecular Weight (Da)
223.27
Molecular Formula
C7H5N5S2
SMILES
C1=C(C(=NC(=C1SC#N)N)N)SC#N
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
