Podophyllotoxin, Microtubule Assembly Inhibitor

Cat. No.
CLIA-0130293
Product Size
500 mg 100 mg Custom Size

Product Overview

Description
Potent, competitive microtubule assembly inhibitor.
Purity
> 90%
Form
Solid
Target
Microtubule assembly
Biological Description
Potent, competitive microtubule assembly inhibitor (IC50 = 5 μM). Prevents the formation of mitotic spindles. Antitumor and keratolytic agent. Active in vivo and in vitro.
Source
Synthetic
CAS Number
518-28-5
Solubility Overview
Slightly soluble in water.

Chemical Properties

Chemical Name
(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Molecular Weight (Da)
414.41
Molecular Formula
C22H22O8
PubChem Identifier
SMILES
COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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