PKC412, Broad Spectrum Protein Kinase Inhibitor

Cat. No.
CLIA-0130180
Product Size
1 mg 5 mg Custom Size

Product Overview

Description
Broad spectrum protein kinase inhibitor.
Purity
> 98%
Form
Solid
Target
Broad spectrum protein kinase
Biological Description
Broad spectrum protein kinase inhibitor. Inhibits PKCα, PKCβ and PKCγ isoforms, PDFRβ, VEGFR2, Syk, PKC, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Antitumor activity. Active in vivo.
Source
Synthetic
CAS Number
120685-11-2
Solubility Overview
Soluble in DMSO to 10 mM.

Chemical Properties

Chemical Name
N-[(5S,6R,7R,9R)-6-Methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]-N-methylbenzamide
Molecular Weight (Da)
570.64
Molecular Formula
C35H30N4O4
PubChem Identifier
SMILES
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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