Phorbol-12,13-dibutyrate, PKC Activator

Inquiry

Cat. No.

CLIA-0130181

Product Size

5 mg 1 mg Custom Size

Product Overview

Description

PKC activator.

Purity

> 98%

Form

Solid

Target

PKC

Biological Description

Protein Kinase C (PKC) activator. Increases kinase phosphorylation, inhibiting Na+,K+-ATPase activity. Induces contraction of vascular smooth muscle.

Source

Synthetic

CAS Number

37558-16-0

Solubility Overview

Soluble in DMSO to 50 mM and in ethanol to 25 mM.

Chemical Properties

Chemical Name

Phorbol-12,13-dibutyrate

Molecular Weight (Da)

504.61

Molecular Formula

C₂₈H₄₀O₈

PubChem Identifier

37783

SMILES

CCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)CCC)O)C

Storage & Handling

Storage Instructions

Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.

Handling

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.