Product Overview
Reactivity
Human, Mouse, Rat, Pig (predicted: Cow, Dog)
Target Information
Alternative Names
Acidic (leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; AN32B_HUMAN; ANP 32B; ANP32B; APRIL; OTTHUMP0000006377; PAL 31; PAL31; PHAPI 2; PHAPI2; PHAPI2 protein; PHAPI2a; Proliferation related acidic leucine rich protein; Putative HLA-DR-associated protein I-2; Silver stainable protein SSP 29; Silver stainable protein SSP29; Silver-stainable protein SSP29; Ssp 29; Ssp29
Function
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Tissue Specificity
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Upon delivery aliquot and store at -20 °C or -80 °C. Avoid repeated freeze / thaw cycles.
Storage Buffer
0.5% Tris, 0.5% BSA. pH: 7.30.
Preservative
0.02% Sodium Azide