Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
A potent small molecule inhibitor of PAK4.
Alternative Names
898044-15-0; UNII-PK459EA5I2
Biological Description
A potent small molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. It binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
Solubility Overview
Soluble to in DMSO to 10 mM.
Chemical Properties
Chemical Name
N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide
Molecular Weight (Da)
490.60
Molecular Formula
C25H30N8OS
SMILES
CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)NC(CN(C)C)C5=CC=CC=C5)SC=C2
Storage & Handling
Storage Instructions
Shipped at 4 °C. Store at -20 °C long term. Store in the dark.
