Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
Potent, selective JAK1 inhibitor.
Alternative Names
Abrocitinib
Biological Description
Potent, selective, orally bioavailable JAK1 inhibitor (IC50 = 29 nM). It displays excellent selectivity for JAK1 versus other JAK family enzymes.
Solubility Overview
> 10 mg/mL in DMSO.
Chemical Properties
Chemical Name
N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide
Molecular Weight (Da)
323.42
Molecular Formula
C14H21N5O2S
SMILES
CCCS(=O)(=O)NC1CC(C1)N(C)C2=NC=NC3=C2C=CN3
Storage & Handling
Storage Instructions
Shipped at 4 °C. Store at -20 °C.
