PCNA Rabbit Polyclonal Antibody

Cat. No.: CLAB-00231316

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human, Mouse, Rat, Common marmoset (predicted: Sheep, Goat, Cow, Dog, Xenopus laevis, Monkey, Zebrafish)
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
Flow Cyt, ICC/IF, IHC-P, WB

Target Information

Target Name
PCNA
UniProt No.
Gene ID
Alternative Names
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNA_HUMAN; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Function
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C or -80 °C. Avoid freeze / thaw cycle.
Storage Buffer
PBSBatches of this product that have a concentration < 1 mg/mL may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. pH: 7.40.
Preservative
0.02% Sodium Azide

For Research Use Only. Not For Clinical Use.

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