Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
ATP-competitive CDK inhibitor.
Biological Description
ATP-competitive CDK inhibitor (IC50 values are 7 (CDC2/cyclin B), 7 (CDK2/cyclin A), 7 (CDK2/cyclin E), 3 (CDK/p35 kinase) and 25 μM (ERK1/p44 MAPK)). Inhibits cell cycle progression in vitro and in vivo.
Solubility Overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM.
Chemical Properties
Chemical Name
6-Benzylamino-2-(2-hydroxyethylamino)-9-methylpurine
Molecular Weight (Da)
298.35
Molecular Formula
C15H18N6O
SMILES
OCCNc1nc(NCc2ccccc2)c2ncn(C)c2n1
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
