Product Size
25 mg
10 mg
Custom Size
Product Overview
Description
Potent, cell-permeable, irreversible non-selective CDC25 inhibitor.
Alternative Names
DA3003-1
Biological Description
Potent, cell-permeable, irreversible non-selective Cdc25 inhibitor. Induces cell cycle arrest at both G1 and G2/M phase. Shows antiproliferative effects against tumor cell lines (IC50 = 0.2-35 μM). Shows antitumor effects in vivo.
Solubility Overview
Soluble in ethanol to 50 mM and in DMSO to 50 mM.
Chemical Properties
Chemical Name
6-Chloro-7-(2-morpholin-4-ylethylamino)quinoline-5,8-dione
Molecular Weight (Da)
321.76
Molecular Formula
C15H16ClN3O3
SMILES
C1COCCN1CCNC2=C(C(=O)C3=C(C2=O)N=CC=C3)Cl
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
