NEK6 Mouse Monoclonal Antibody

Cat. No.: CLAB-00231209

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype

IgG1

Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Conjugation

Unconjugated

Applications

IHC-P, WB

Target Information

Target Name

NEK6

UniProt No.

Q9HC98

Gene ID

10783

Alternative Names

Highly similar to cell cycle protein kinase CDC5/MSD2; NEK6; NEK6_HUMAN; Never in mitosis A-related kinase 6; NIMA (Never In Mitosis Gene A) Related Kinase 6; NimA related protein kinase 6; NimA-related protein kinase 6; Protein kinase SID6 1512; Protein kinase SID6-1512; Putative serine threonine protein kinase; Serine/threonine protein kinase Nek6; Serine/threonine-protein kinase Nek6; SID6 1512; SID61512

Function

Activated during M phase. Required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis. Phosphorylates KIF11 to promote mitotic spindle formation.

Tissue Specificity

Ubiquitous, with highest expression in heart and skeletal muscle.

Shipping & Handling

Shipping

Shipped on dry ice.

Storage

Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle.

Storage Buffer

PBS, 1% BSA, 50% Glycerol. pH: 7.30.

Preservative

0.02% Sodium Azide

For Research Use Only. Not For Clinical Use.