Product Size
50 mg
250 mg
Custom Size
Product Overview
Description
Selective, non-competitive and reversible IMPDH inhibitor. Immunosuppressant agent.
Biological Description
Selective, non-competitive and reversible IMPDH inhibitor (IC50 = 3 μM). Immunosuppressant agent. Inhibits guanosine synthesis. Shows antiparasitic effects and suppresses T cells and B cells in vivo. Orally active.
Solubility Overview
Soluble in DMSO to 50 mM.
Chemical Properties
Chemical Name
2-Morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
Molecular Weight (Da)
433.49
Molecular Formula
C23H31NO7
SMILES
C12=C(C(=C(C(=C1O)C/C=C(/CCC(OCCN3CCOCC3)=O)C)OC)C)COC2=O
Storage & Handling
Storage Instructions
Store at 4 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
