Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
A potent, cell-permeable, small molecule mitosis inhibitor.
Biological Description
A potent, cell-permeable, small molecule mitosis inhibitor. It arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC50 = 14 μM).
Solubility Overview
DMSO (> 25 mg/mL) or EtOH (> 5 mg/mL).
Chemical Properties
Chemical Name
ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate
Molecular Weight (Da)
292.35
Molecular Formula
C14H16N2O3S
SMILES
CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
Storage & Handling
Storage Instructions
Shipped at 4 °C. Store at -20 °C. Store in the dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
