MK2 Rabbit Polyclonal Antibody

Cat. No.: CLAB-00231168

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
ICC/IF, WB

Target Information

Target Name
MAPKAPK2
UniProt No.
Gene ID
Alternative Names
MAP kinase activated protein Kinase 2; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPK2_HUMAN; MAPKAP K2; MAPKAP kinase 2; MAPKAPK 2; MAPKAPK-2; MAPKAPK2; Mitogen activated protein kinase activated protein kinase 2; MK 2; MK2
Function
Its physiological substrate seems to be the small heat shock protein. In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase. This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X-S, where Hyd is a large hydrophobic residue. Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.
Tissue Specificity
Expressed in all tissues examined.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Stable for 12 months at -20 °C.
Storage Buffer
49% PBS, 0.88% Sodium chloride, 50% GlycerolPBS without Mg2+ and Ca2+. pH: 7.40.
Preservative
0.02% Sodium Azide

For Research Use Only. Not For Clinical Use.

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