MAD1L1/MAD1 Rabbit Polyclonal Antibody

Cat. No.: CLAB-00231143

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Saccharomyces cerevisiae
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
ICC/IF, WB

Target Information

Target Name
MAD1L1
UniProt No.
Gene ID
Alternative Names
hMAD1; HsMAD1; MAD1; MAD1 mitotic arrest deficient like 1 (yeast); MAD1-like protein 1; MAD1L1; MD1L1_HUMAN; Mitotic arrest deficient 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; PIG9; Tax binding protein 181; Tax-binding protein 181; TP53I9; Tumor protein p53 inducible protein 9; TXBP181
Function
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
Tissue Specificity
Expressed weakly at G0/G1 and highly at late S and G2/M phase.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Upon delivery aliquot and store at -20 °C or -80 °C. Avoid repeated freeze / thaw cycles.
Storage Buffer
Whole serum.
Preservative
0.1% Sodium Azide

For Research Use Only. Not For Clinical Use.

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