Product Size
10 mg
5 mg
Custom Size
Product Overview
Description
CDK2, GSK3β and LCK inhibitor.
Biological Description
CDK2, GSK3β and LCK inhibitor (IC50 values are 0.67, 0.23 and 0.47 μM for CDK2, GSK3β and LCK, respectively). Antiproliferative activity in vitro.
Solubility Overview
Soluble in DMSO to 25 mM.
Chemical Properties
Chemical Name
9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one
Molecular Weight (Da)
327.18
Molecular Formula
C16H11BrN2O
SMILES
O=C1Nc2ccccc2c2[nH]c3ccc(Br)cc3c2C1
Storage & Handling
Storage Instructions
Store at 4 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
