Product Size
1 mg
5 mg
Custom Size
Product Overview
Description
Potent, cell-permeable protein kinase C inhibitor.
Biological Description
Potent, cell-permeable protein kinase C (PKC) inhibitor (IC50 are 2.45 and 25.7 μM for PKC and PKA respectively). Cytotoxic and antitumor agent. Active in vitro and in vivo.
Solubility Overview
Soluble in DMSO to 25 mM.
Chemical Properties
Chemical Name
6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one
Molecular Weight (Da)
311.34
Molecular Formula
C20H13N3O
SMILES
C1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=CC=CC=C6N5
Storage & Handling
Storage Instructions
Store at 4 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
