Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
Selective σ1 antagonist.
Alternative Names
1-(4-iodophenyl)-3-(2-adamantyl)guanidine
Biological Description
Selective σ1 antagonist (Ki = 8 μM). Shows GTP- and suramin-sensitive affinity binding. Induces cell death and inhibits tumor growth. Active in vitro and in vivo.
Solubility Overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM.
Chemical Properties
Chemical Name
N-(4-Iodophenyl)-N'-tricyclo[3.3.1.13,7]dec-2-ylguanidine
Molecular Weight (Da)
395.29
Molecular Formula
C17H22IN3
SMILES
C1C2CC3CC1CC(C2)C3N=C(N)NC4=CC=C(C=C4)I
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
