Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
PRMT1 inhibitor.
Biological Description
PRMT1 inhibitor (IC50 values are 4.8 μM and 22 for hPRMT1 and RmtA, respectively). Docks in both binding sites of the histone arginine methyltransferase pocket.
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
4-Amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
Molecular Weight (Da)
820.70
Molecular Formula
C20H7Br6NO5
SMILES
O=C(O)c4cc(Br)c(N)c(Br)c4C=2c3cc(Br)c(O)c(Br)c3OC=1C=2C=C(Br)C(=O)C=1Br
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
