Product Size
25 mg
5 mg
Custom Size
Product Overview
Description
Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor.
Target
CK1delta and CK1epsilon
Biological Description
Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor. Induces cell cycle arrest and apoptosis. Selectively inhibits tumor cells growth. Shows antitumor effects in vivo.
Solubility Overview
Soluble in DMSO to 50 mM.
Chemical Properties
Chemical Name
(3Z)-1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
Molecular Weight (Da)
311.33
Molecular Formula
C18H17NO4
SMILES
COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC
Storage & Handling
Storage Instructions
Store at -20 °C. It is important to note that this product is reported to be light sensitive. Store in the dark. Store under desiccating conditions.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
