Product Size
10 x 96 tests
Custom Size
Product Information
Sample Type
Cell Lysate, Tissue Lysate
Range
7.8 pg/mL-1000 pg/mL
Target Information
Function
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
Sequence Similarities
Contains 1 MATH domain.
Alternative Names
4732496E14Rik; EBI6; EBV induced protein 6; Epstein-Barr virus-induced protein 6; MGC:10353; Tnf receptor associated factor 1; TNF receptor-associated factor 1; TRAF 1; TRAF1; TRAF1_HUMAN
Shipping & Handling
Shipping
Shipped on dry ice.
Storage Instructions
Store at 4 °C. Please refer to protocols.