Human KRT13 Knockout A-431 Cell Lysate

Cat. No.
CLCP-00350557
Product Size
1 Kit

Product Overview

Parental Cell Line
A431
Biosafety Level
BSL-2
Species
Human
Mutation Description
Knockout achieved by CRISPR/Cas9; X = 5 bp deletion; Frameshift: 100%
Knockout Validation
Next Generation Sequencing (NGS), Western Blot (WB)
Tested Applications
WB

Cell Line Properties

Tissue
Epidermoid carcinoma
Morphology
Epithelial
Gender
Female
Form
Liquid
Mycoplasma Free
Yes

Target Information

Gene Name
KRT13
Gene ID
UniProt No.
Gene Function
Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2 (By similarity).
Sequence Similarities
Belongs to the intermediate filament family.
Post-translational Modifications
O-glycosylated; glycans consist of single N-acetylglucosamine residues.

Storage & Handling

Cryopreservation Cell Medium
Cell freezing medium - DMSO serum free media, contains 8.7% DMSO in MEM supplemented with methyl cellulose.
Culture Medium
McCoY5a + 10% FBS
Initial Handling Guidelines
Lyophilizate may be stored at 4 °C. After reconstitution, store at -20 °C for short-term storage or -80 °C for long-term storage.
Storage Instructions
Store at -80 °C. Avoid freeze / thaw cycles.

For Research Use Only. Not For Clinical Use.

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