Human KRT1 Knockout MCF-7 Cell Line

Cat. No.
CLCP-00350202
Product Size
1 x 106 cells/vial, 1 mL

Product Overview

Parental Cell Line
MCF-7
Biosafety Level
BSL-1
Species
Human
Knockout Validation
Sanger Sequencing, Western Blot (WB)

Cell Line Properties

Tissue
Breast adenocarcinoma
Morphology
Epithelial
Viability
~80%
Adherent / Suspension
Adherent
Gender
Female

Target Information

Gene Name
KRT1
Gene ID
UniProt No.
Gene Function
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1).
Sequence Similarities
Belongs to the intermediate filament family.
Post-translational Modifications
Undergoes deimination of some arginine residues (citrullination).

Storage & Handling

Recommended Control
Human wild-type MCF-7 cell line.
Cryopreservation Cell Medium
Cell freezing medium - DMSO serum free media, contains 8.7% DMSO in MEM supplemented with methyl cellulose.
Culture Medium
MEM + 10% FBS + 0.01 mg/mL bovine insulin
Storage Instructions
Shipped on dry ice. Store in liquid nitrogen.
Storage Buffer
Constituents: 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether.

For Research Use Only. Not For Clinical Use.

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