Human DLL3 Knockout MCF-7 Cell Line

Cat. No.
CLCP-00350126
Product Size
1 x 106 cells/vial, 1 mL

Product Overview

Parental Cell Line
MCF-7
Biosafety Level
BSL-1
Species
Human
Knockout Validation
Sanger Sequencing

Cell Line Properties

Tissue
Breast adenocarcinoma
Morphology
Epithelial
Viability
~80%
Adherent / Suspension
Adherent
Gender
Female

Target Information

Gene Name
DLL3
Gene ID
UniProt No.
Gene Function
Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Sequence Similarities
Contains 1 DSL domain.Contains 6 EGF-like domains.
Post-translational Modifications
Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.

Storage & Handling

Recommended Control
Human wild-type MCF-7 cell line.
Cryopreservation Cell Medium
Cell freezing medium - DMSO serum free media, contains 8.7% DMSO in MEM supplemented with methyl cellulose.
Culture Medium
MEM + 10% FBS + 0.01 mg/mL bovine insulin
Storage Instructions
Shipped on dry ice. Store in liquid nitrogen.
Storage Buffer
Constituents: 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether.

For Research Use Only. Not For Clinical Use.

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