Product Size
1 x 96 tests
Custom Size
Product Information
Sample Type
Cell Culture Supernatant, Serum, Cell Culture Extracts, Cell Culture Media, Hep Plasma, Edta Plasma, Cit Plasma
Assay Type
Sandwich (quantitative)
Range
7.81 pg/mL-500 pg/mL
Detection Method
Colorimetric
Target Information
Function
May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
Sequence Similarities
Belongs to the pancreatic ribonuclease family.
Alternative Names
ALS9; AMYOTROPHIC LATERAL SCLEROSIS; ANG; ANG 1; ANG I; ANG1; ANGI; ANGI_HUMAN; Angiogenin; Angiogenin ribonuclease RNase A family, 5; Epididymis luminal protein 168; HEL168; MGC22466; MGC71966; Ribonuclease 5; Ribonuclease RNase A Family 5; RNase 5; RNASE4; RNASE5
Tissue Specificity
Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage Instructions
Store at 4 °C. Please refer to protocols.
