Helenalin, NF-kappaB Inhibitor

Cat. No.
CLIA-0130085
Product Size
500 μg 100 μg Custom Size

Product Overview

Description
NF-κB inhibitor.
Purity
> 95%
Form
Solid
Target
NF-kappaB
Biological Description
NF-κB inhibitor. Induces apoptosis. Shows anti-inflammatory and antineoplastic effects. Shows hepatoprotective effects in vivo. Orally active.
Source
Synthetic
CAS Number
6754-13-8
Solubility Overview
Soluble in ethanol (up to 10 mg/mL) and in DMSO (up to 20 mg/mL).

Chemical Properties

Chemical Name
(3aR,5R,5aR,8aR,9S,9aS)-9-Hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione
Molecular Weight (Da)
262.30
Molecular Formula
C15H18O4
PubChem Identifier
SMILES
C[C@@H]1C[C@@H]2[C@H]([C@@H]([C@]3([C@H]1C=CC3=O)C)O)C(=C)C(=O)O2

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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