Product Size
20 mM/mL
100 mM/mL
Custom Size
Product Overview
Description
ROCK2 inhibitor. 1 mL water soluble pack.
Alternative Names
Fasudil
Biological Description
ROCK2 inhibitor (IC50 = 1.9 µM). Also shown to inhibit PRK2 (IC50 = 4 µM), MSK1 (IC50 = 5 µM), Rsk2 (IC50 = 15 µM), PKA, p70 S6 Kinase, CaM Kinase and MLCK. Calcium antagonist and vasodilator.Soluble in 1 mL water to give specified mM/mL concentration.
Solubility Overview
Soluble in 1 mL of water to give specified mM/mL concentration.
Chemical Properties
Chemical Name
1-(5-Isoquinolinylsulfonyl)homopiperazine hydrochloride
Molecular Weight (Da)
327.83
Molecular Formula
C14H17N3O2S.HCl
SMILES
Cl.O=S(=O)(c2cccc1cnccc12)N3CCCNCC3
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
