Product Size
100 mg
25 mg
Custom Size
Product Overview
Description
Potent, specific deoxycytidine analog.
Alternative Names
LY188011
Biological Description
Potent specific, deoxycytidine analog. Pro-drug phosphorylated by deoxycytidine kinase to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). Cell cycle specific, inhibits the S and G1 phase. Antitumor activity in vitro and in vivo.
Solubility Overview
Soluble in water to 100 mM and in DMSO to 50 mM.
Chemical Properties
Chemical Name
2'-Deoxy-2',2'-difluorocytidine hydrochloride
Molecular Weight (Da)
299.66
Molecular Formula
C9H11F2N3O4.HCl
SMILES
C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl
Storage & Handling
Storage Instructions
Store at -20 °C. It is important to note that this product is reported to be light sensitive. Store in the dark. Store under desiccating conditions.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
