Erastin, Ferroptosis Activator

Inquiry

Cat. No.

CLIA-0130103

Product Size

1 mg 5 mg Custom Size

Product Overview

Description

Selective ferroptosis activator.

Purity

> 98%

Form

Solid

Target

Ferroptosis

Biological Description

Selective ferroptosis activator. Induces RAS-RAF-MEK-dependent non-apoptotic cell death via VDAC2 (IC50 = 0.1 μM).

Source

Synthetic

CAS Number

571203-78-6

Solubility Overview

Soluble in DMSO to 20 mM.

Chemical Properties

Chemical Name

2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone

Molecular Weight (Da)

547.04

Molecular Formula

C₃₀H₃₁ClN₄O₄

PubChem Identifier

11214940

SMILES

CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl

Storage & Handling

Storage Instructions

Shipped at 4 °C. Store at -20 °C long term. It is important to note that this product is reported to be light sensitive. Store under desiccating conditions.

For Research Use Only. Not For Clinical Use.