Product Size
100 mg
25 mg
Custom Size
Product Overview
Description
Potent 11β-HSD1 inhibitor.
Alternative Names
Emodol, Frangula emodin, Schuttgelb
Biological Description
Emodin, an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. It has a role as a tyrosine kinase inhibitor, an antineoplastic agent, a laxative and a plant metabolite.
Solubility Overview
Soluble in DMSO to 50 mM.
Chemical Properties
Chemical Name
1,3,8-Trihydroxy-6-methylanthracene-9,10-dione
Molecular Weight (Da)
270.24
Molecular Formula
C15H10O5
SMILES
CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O
Storage & Handling
Storage Instructions
Store at -20 °C (desiccating conditions).
