Product Size
1 x 96 tests
Custom Size
Product Information
Sample Type
Tissue, Cell Lysate
Assay Type
Sandwich (quantitative)
Range
117.188 pg/mL-7500 pg/mL
Detection Method
Colorimetric
Target Information
Function
Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Sequence Similarities
Contains 2 CH (calponin-homology) domains. Contains 22 spectrin repeats. Contains 1 WW domain. Contains 1 ZZ-type zinc finger.
Alternative Names
BMD; CMD3B; DMD; DMD_HUMAN; Duchenne muscular dystrophy protein; Dystrophin; Muscular dystrophy Duchenne and Becker types
Tissue Specificity
Expressed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma. Expressed in brain, muscle, kidney, lung and testis. Isoform 5 is expressed in heart, brain, liver, testis and hepatoma cells. Most tissues contain transcripts of multiple isoforms, however only isoform 5 is detected in heart and liver.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage Instructions
Store at 4 °C. Please refer to protocols.
