Product Size
10 g
5 g
Custom Size
Product Overview
Description
Non-selective phosphodiesterase (PDE) inhibitor.
Target
Non-selective phosphodiesterase (PDE)
Biological Description
Non-selective phosphodiesterase (PDE) inhibitor. Exerts antiplatelet, anti-inflammatory, antioxidative and antifibrotic effects. Inhibits hydrolysis of cyclic AMP (cAMP) and cGMP (IC50 = 5 and 3 μM, respectively) in vitro.
Solubility Overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM.
Chemical Properties
Chemical Name
2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
Molecular Weight (Da)
504.63
Molecular Formula
C24H40N8O4
SMILES
OCCN(CCO)c2nc1c(nc(nc1c(n2)N3CCCCC3)N(CCO)CCO)N4CCCCC4
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
