Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
Potent FAK inhibitor.
Alternative Names
PF-04554878; VS-6063
Biological Description
Potent FAK inhibitor. Prevents tumor invasion and dissemination. Preferentially targets cancer stem cells in mouse xenograft models. Orally bioavailable.
Solubility Overview
Soluble in DMSO to 25 mM.
Chemical Properties
Chemical Name
N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
Molecular Weight (Da)
510.49
Molecular Formula
C20H21F3N8O3S
SMILES
CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F
Storage & Handling
Storage Instructions
Shipped at room temperature. Store at -20 °C. Store under desiccating conditions.
