Product Size
50 mg
250 mg
Custom Size
Product Overview
Description
JNK1 inhibitor.
Biological Description
JNK1 inhibitor. Selectivity data showed that DB07268 had some degree of selectivity over quite a few kinases with the exceptions of PLK, CHK1, and CK2. Although it showed submicromolar potency against these three kinases, it still appeared to exhibit at least 70- to 90-fold greater potency against JNK1 than PLK, CHK1, and CK2.
Solubility Overview
≥ 15.2 mg/mL in DMSO, insoluble in EtOH, insoluble in H2O.
Chemical Properties
Chemical Name
2-[[2-(3-hydroxyanilino)pyrimidin-4-yl]amino]benzamide
Molecular Weight (Da)
321.33
Molecular Formula
C17H15N5O2
SMILES
C1=CC=C(C(=C1)C(=O)N)NC2=NC(=NC=C2)NC3=CC(=CC=C3)O
Storage & Handling
Storage Instructions
Shipped at room temperature. Store at -20 °C.
