Product Size
250 mg
50 mg
Custom Size
Product Overview
Description
Flavonoid. Lipooxygenase inhibitor. Antioxidant, anti-inflammatory agent.
Alternative Names
Diferuloylmethane
Biological Description
Flavonoid derived from Curcuma longa plant. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC50 values are 8 and 52 μM, respectively). Blood-brain barrier permeable. Shows diverse range of actions including free radical scavenging activity in vitro and in vivo, cardio and neuroprotective effects.
Solubility Overview
Soluble in ethanol to 10 mM and in DMSO to 10 mM.
Chemical Properties
Chemical Name
(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
Molecular Weight (Da)
368.38
Molecular Formula
C21H20O6
SMILES
COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
